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目的:对比分析培哚普利与美托洛尔在糖尿病无症状心功能不全治疗中的具体疗效。方法:选取80例糖尿病无症状心功能不全患者,依据数字随机表法将其列入观察组与对照组各40例。观察组和对照组分别使用培哚普利与美托洛尔进行临床治疗。结果:治疗后,两组左室射血分数、B型尿钠肽、心肌做功指数比较,差异均有统计学意义(P均<0.05);两组不良反应的发生率比较,差异无统计学意义(P>0.05)。结论:在糖尿病无症状心功能不全的治疗中,与美托洛尔比较,培哚普利的应用效果更好,可推广。
OBJECTIVE: To compare and analyze the specific efficacy of perindopril and metoprolol in the treatment of asymptomatic cardiac dysfunction in diabetes mellitus. Methods: Eighty patients with asymptomatic diabetic heart failure were enrolled in this study. They were enrolled in observation group and control group according to the digital random table method. The observation group and the control group were treated with perindopril and metoprolol respectively. Results: After treatment, the left ventricular ejection fraction, B-type natriuretic peptide and myocardial work index were significantly different between the two groups (all P <0.05). There was no significant difference between the two groups in the incidence of adverse reactions Significance (P> 0.05). CONCLUSION: In the treatment of asymptomatic cardiac dysfunction in diabetic patients, compared with metoprolol, the application of perindopril is better and can be promoted.