腹腔肿瘤侵犯肠系膜上动脉后，根治性手术切除仍为其唯一可治愈手段。然而，联合动脉切除与重建的手术难度大，手术并发症发生率和手术死亡率高，历来被视为外科手术 “禁区”。随着器官体外保存和移植技术的发展，自体小肠移植技术应运而生。该技术主要涉及离体小肠体外保存、病变部位切除和正常小肠植回体内等环节。自体小肠移植技术突破了传统手术肠系膜上动脉无法切除重建或重建效果不佳的临床难题。现阶段该技术仍存在诸多问题，笔者结合团队临床实践及经验教训，探索自体小肠移植技术的实践与挑战。笔者团队认为：自体小肠移植技术是治疗包绕肠系膜上动脉肿瘤的可行手段，术后并发症可控，值得进一步探索和积累经验。“,”Radical surgical resection offers curable treatment for abdominal neoplasms involving the superior mesenteric artery (SMA). However, the combined SMA resection with reconstruction has remained a technically difficult procedure with high morbidity and mortality, which has been regarded as a surgically forbidden area. With advances in organ preservation and transplantation techniques, intestinal autotransplantation has recently emerged in clinical practice as a treatment option for neoplasms involving SMA. The operative procedure includes n in vitro preservation of a segment of small intestine as the autograft, n en bloc resection of the neoplasm along with involved organs, and autotransplantation of the intestine autograft. This technique has expanded eligibility for resection of otherwise unresectable lesions involving SMA. In our opinion, intestinal autotransplantation appears to be technically feasible in abdominal neoplasms encasing SMA with an acceptable morbidity and mortality. This novel technique is thus worthy of further investigation and accumulation of experience.n