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近年发现羊水中有多种酶,尤其是转氨酶,是一种指示细胞损伤极为敏感的标志,因此可用来确诊子宫内胎儿的活动及危险情况。作者研究了正常与异常妊娠时羊水转氨酶情况,对象为75例有明确的末月经孕28～40周的孕妇。A 组为正常妊娠25例,B 组为异常妊娠50例,其中妊毒症15例,子痫9例,过期妊娠7例、双胎12例,羊水过多4例,Rh 血型不合3例。羊水来源于剖腹产时羊膜穿刺或人工破膜时。标本收集后4～6小时内用 Reit-man 及 Grankel 氏比色法进行生化测定,结果:正常妊娠 GOT 范围为7.9～14.8 KU/ml,平均为11.8±2.40KU/ml/分,GPT 范围为4.0～10.0KU/ml,平均为6.7±1.75 KU/ml/分,其数值大小与产母年龄、孕次、社会经济状况、胎儿性别和胎盘重量无关,但随孕期的进展和胎儿体重的增长、酶活性有显著升高。在异常妊娠,如过期妊娠,先兆子痫,子痫病
In recent years, amniotic fluid found in a variety of enzymes, especially transaminases, is a sign of cell injury is extremely sensitive to the signs, it can be used to confirm the activities of the fetus and the risk of the situation. The authors studied the amniotic fluid transaminase in normal and abnormal pregnancies for 75 pregnant women who had a definite end-stage menstrual period of 28 to 40 weeks. A group of 25 cases of normal pregnancy, B group of 50 cases of abnormal pregnancy, including 15 cases of pregnancy-induced eclampsia, eclampsia in 9 cases, 7 cases of premature pregnancy, twins in 12 cases, 4 cases of polyhydramnios, Rh blood group incompatibility in 3 cases. Amniotic fluid from cesarean section when amniocentesis or artificial rupture of membranes. The results of biochemical detection by Reit-man and Grankel colorimetry within 4 to 6 hours after collection of the specimens showed that the normal pregnancy GOT ranged from 7.9 to 14.8 KU / ml with an average of 11.8 ± 2.40 KU / ml / min with a GPT range of 4.0 ~ 10.0KU / ml, an average of 6.7 ± 1.75 KU / ml / min, the value of the size and age of mother, pregnancy time, socioeconomic status, fetal sex and placental weight independent, but with the progress of pregnancy and fetal weight gain , Enzyme activity was significantly increased. In abnormal pregnancy, such as overdue pregnancy, preeclampsia, eclampsia