糖尿病黄斑水肿(DME)是糖尿病眼部并发症中对视力损伤最严重的致盲性眼病。随着饮食结构及生活模式的改变,糖尿病患者的人数不断增加,因此对DME的发病机制及相关性因素的研究至关重要。本文就糖尿病黄斑水肿的发病机制及相关性因素研究概况综述如下。1血-视网膜屏障的破坏关于DME的研究大多数学者着眼于血-视网膜屏障的破坏,认为糖尿病患者长期代谢紊乱,血管功能改变,进而引起血-视网膜屏障的破坏,血管渗漏最终导致黄斑水 Diabetic macular edema (DME) is the most eye-catching blinding eye disease in diabetic ocular complications. With the change of diet structure and life style, the number of patients with diabetes continues to increase, so the study on the pathogenesis and related factors of DME is very important. In this paper, the pathogenesis of diabetic macular edema and related factors are summarized as follows. 1 Blood-Retinal Barrier Damage Research on DME Most scholars focus on the destruction of the blood-retinal barrier, which suggests that long-term metabolic disorders and vascular changes in patients with diabetes, which in turn lead to the destruction of the blood-retinal barrier, eventually leading to macular water leakage