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目的探讨连续性血液净化对老年急性肾功能衰竭(ARF)患者肾功能及生存质量的影响。方法选择老年ARF患者78例,依照建档顺序分组,每组39例。观察组采取连续性血液净化疗法治疗,对照组采取间歇性血液净化疗法治疗。治疗1个月后,比较两组肾功能指标[尿素氮(BUN)、血肌酐(Scr)]与血流动力学指标[动脉血氧分压(PO2)、动脉血二氧化碳分压(PCO2)、酸碱度]及生存质量评分,并评估两组临床疗效。结果治疗后,观察组BUN、Scr、PCO2水平均较对照组降低,PO2、酸碱度及生存质量评分均较对照组提高,差异有统计学意义(P<0.05)。观察组总有效率为82.05%(32/39),对照组为61.54%(24/39),两组比较差异有统计学意义(P<0.05)。结论老年急性肾功能衰竭应用连续性血液净化疗法治疗效果显著,可改善肾功能,提升患者生存质量。
Objective To investigate the effects of continuous blood purification on renal function and quality of life in elderly patients with acute renal failure (ARF). Methods 78 elderly patients with ARF were selected and divided into groups according to the order of filing, with 39 cases in each group. Observation group to take continuous blood purification therapy, control group to take intermittent blood purification therapy. One month after treatment, the changes of renal function indexes (BUN, Scr) and hemodynamics [PO2, PCO2, PH] and quality of life scores, and to assess the clinical efficacy of both groups. Results After the treatment, the levels of BUN, Scr and PCO2 in the observation group were lower than those in the control group. The scores of PO2, pH, and quality of life were all higher in the observation group than those in the control group (P <0.05). The total effective rate was 82.05% (32/39) in the observation group and 61.54% (24/39) in the control group, with significant difference between the two groups (P <0.05). Conclusion Acute renal failure in elderly patients with continuous blood purification therapy is significant, can improve renal function, improve patient quality of life.