资料曾有过一些报道,提到口服甾体避孕药与其他药物之间的相互作用。这些作用可导致避孕效果的降低,同时也可影响其他药物的代谢和药理活性。口服避孕药与强力诱导肝微粒体酶产生的药物同用,可导致口服避孕药对月经周期失去控制或引起妊娠。这些药物包括:苯巴比妥、利福平和苯妥英钠;其他一些镇痉剂和巴比妥类药物也偶见报道。由于刺激了这些酶的生成,增加了口服避孕药 There have been some reports on the data, referring to the interaction between oral steroidal contraceptives and other drugs. These effects can lead to a reduction in contraceptive effectiveness as well as to the metabolic and pharmacological activities of other drugs. Oral contraceptives and drugs induced by strong induction of liver microsomal enzymes can cause oral contraceptives to lose control of the menstrual cycle or cause pregnancy. These include phenobarbital, rifampicin and phenytoin; other antispasmodic agents and barbiturates are occasionally reported. Oral contraceptives have been added by stimulating the production of these enzymes