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目的探讨慢性阻塞性肺疾病(COPD)患者的认知功能,从而明确患者认知功能的相应变化以及认知功能损害的有关因素。方法采用简易精神智能检测测定量表来选择我院60例稳定期COPD患者进行气血参数以及肺功能的测定,同时选择该地区60例健康居民作为对照组。然后根据动脉血氧分压值(PaO2)以及FEV1占预测值百分比将患者进行分组。两组之间的年龄、性别以及受教育程度没有明显差异性,不存在统计学意义。结果CPOD组患者和对照组进行比较,COPD组患者的简易精神了智能检测测定量表的总分、学习、记忆、计算以及结构分数测评都要明显低于对照组。PaO2≥60mmHg的对照记忆力、计算力以及学习能力测验评分都要高于PaO2<60mmHgCOPD组患者的评分。FEV1占预测值百分比≥50%COPD组和FEV1占预测值百分比<50%对照组数据比较不存在统计学意义。结论稳定期的COPD患者进的简易精神智能检测测定量表的总分明显要低于对照组,主要表现在学习、记忆、计算以及结构等方案,因此说COPD患者有明显的认知功能障碍,需要对其进行及时治疗,从而更好的满足患者及其家属的治疗需求。
Objective To explore the cognitive function of patients with chronic obstructive pulmonary disease (COPD) so as to clarify the corresponding changes of cognitive function and related factors of cognitive impairment in patients. Methods Sixty patients with stable COPD in our hospital were enrolled in this study. The blood parameters and lung function were measured by the simple mental intelligence test, and 60 healthy residents in the district were selected as the control group. Patients were then grouped according to the arterial partial pressure of oxygen (PaO2) and the percentage of predicted FEV1. There was no significant difference in age, sex and educational attainment between the two groups, with no statistical significance. Results Compared with the control group, CPOD group patients’ scores of mental retardation, learning, memory, calculation and structure score were all significantly lower than those of the control group. PaO2 ≥ 60mmHg control memory, computational power and learning ability test scores were higher than PaO2 <60mmHgCOPD patients score. FEV1 as a percentage of predicted value ≥50% COPD group and FEV1 as a percentage of predicted value <50% Data from the control group were not statistically significant. Conclusions The total score of simple mental intelligence test in stable COPD patients was significantly lower than that of the control group, mainly in the study, memory, calculation and structure programs, so that COPD patients have obvious cognitive dysfunction, Need to be treated promptly to better meet the treatment needs of patients and their families.