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目的:探讨腹腔镜手术配合米非司酮治疗子宫内膜异位症的临床效果。方法:2009年1月~2012年1月我院共治疗子宫内膜异位症64例,均行腹腔镜手术,其中32例同时予以米非司酮治疗,设立为观察组,另选择同期未予米非司酮治疗的32例患者,设立为对照组。结果:术后随访3~12个月,观察组20例术后第1个月恢复月经,痛经消失,1例术后自觉症状无明显改善,1例术后B超6个月再次发现盆腔包块。1例怀孕。对照组8例症状无改善。观察组患者总有效率达93.75%,对照组患者总有效率达75.00%,两组疗效比较存在显著性差异(P<0.05)。结论:腹腔镜手术配合米非司酮治疗子宫内膜异位症可以提高疗效,不良反应少,且提高受孕率,值得推广和应用。
Objective: To investigate the clinical effect of laparoscopic surgery combined with mifepristone in the treatment of endometriosis. Methods: From January 2009 to January 2012, 64 cases of endometriosis were treated in our hospital. All patients underwent laparoscopic surgery. 32 of them were treated with mifepristone at the same time. To mifepristone treatment of 32 patients, set up as a control group. Results: All cases were followed up for 3 to 12 months. In the observation group, 20 cases recovered menstruation and disappeared dysmenorrhoea in the first month after operation, and no significant improvement was found in one case after operation. One case found pelvic package again after 6 months Piece. 1 case of pregnancy. 8 cases in the control group showed no improvement in symptoms. The total effective rate was 93.75% in the observation group and 75.00% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: Laparoscopic surgery combined with mifepristone in the treatment of endometriosis can improve the curative effect, less adverse reactions, and improve the pregnancy rate, it is worth to promote and apply.