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目的探讨缺铁性贫血(IDA)对患者血小板数值的影响和铁剂治疗后血小板数值的变化。方法对2013年7月至2014年3月就诊的129例初诊IDA患者(IDA组)铁剂治疗前后以及119例正常健康体检者(正常对照组)进行血小板数量的检测,并进行比较分析。结果正常对照组血小板值为(213.445 4±44.421 8)×109/L,IDA组血小板值为(301.868 2±109.521 6)×109/L,IDA组血小板值明显高于正常对照组,差异有统计学意义(t=8.206,P<0.01)。IDA组中经铁剂治疗的26例患者,治疗前血小板值为(312.500 0±133.005 6)×109/L,口服琥珀酸亚铁治疗至血红蛋白正常后测得血小板值为(278.346 2±110.200 0)×109/L,铁剂治疗后血小板值低于治疗前,差异有统计学意义(t=2.677,P<0.05)。结论初诊IDA患者的平均血小板水平高于正常人,经铁剂治疗达血红蛋白正常后血小板水平会下降。
Objective To investigate the effect of iron deficiency anemia (IDA) on platelet count and platelet count after iron treatment. Methods The platelet counts of 129 newly diagnosed IDA patients (IDA group) from July 2013 to March 2014 and 119 normal healthy controls (normal control group) were detected and compared. Results The platelet count of the normal control group was (213.445 4 ± 44.421 8) × 109 / L, the platelet count of IDA group was (301.868 2 ± 109.521 6) × 109 / L, and the platelet count of IDA group was significantly higher than that of the normal control group Significance (t = 8.206, P <0.01). In the IDA group, the platelet count (312.500 0 ± 133.005 6) × 109 / L after treatment with iron in the IDA group was (278.346 2 ± 110.200 0) after treatment with ferrous succinate until hemoglobin was normal ) × 109 / L, the platelet value after iron treatment was lower than before treatment, the difference was statistically significant (t = 2.677, P <0.05). Conclusions The average platelet level of newly diagnosed IDA patients is higher than that of normal people, and the level of platelets will decrease after the treatment of iron with hemoglobin.