论文部分内容阅读
目的探讨十二指肠乳头局部喷洒肾上腺素对经内镜逆行胰胆管造影(ERCP)术后胰腺炎的预防效果。方法选取我院收治的行ERCP手术治疗的患者128例作为研究对象,采取随机数字表将其分成观察组和对照组,各64例。观察组于手术结束前在十二指肠乳头局部喷洒肾上腺素,对照组不给予肾上腺素处理。比较两组术后胰腺炎发生情况、手术前后血淀粉酶水平。结果两组术前血淀粉酶比较,差异无统计学意义(P>0.05),术后6 h、24 h均有明显上升,但观察组术后6 h、24 h血淀粉酶水平均显著低于同时点对照组,差异有统计学意义(P<0.05);观察组高淀粉酶血症、胰腺炎发生率分别为7.81%、1.56%,均显著低于对照组,差异有统计学意义(P<0.05)。结论 ERCP手术结束前于十二指肠乳头局部喷洒肾上腺素可有效防止术后胰腺炎以及高淀粉酶血症的发生。
Objective To investigate the preventive effect of local injection of epinephrine by duodenal papilla on pancreatitis after endoscopic retrograde cholangiopancreatography (ERCP). Methods A total of 128 patients undergoing ERCP surgery admitted to our hospital were selected as the research object. Random number table was used to divide them into observation group and control group, with 64 cases in each group. In the observation group, epinephrine was sprayed locally on the duodenal papilla before the end of surgery, while the control group was given no adrenaline treatment. The incidence of pancreatitis was compared between the two groups before and after blood amylase levels. Results There was no significant difference in preoperative serum amylase between the two groups (P> 0.05), and the levels of serum amylase were significantly increased at 6 and 24 h after operation in both groups (P <0.05). The incidences of hypermylase and pancreatitis in the observation group were 7.81% and 1.56%, respectively, which were significantly lower than those in the control group (P <0.05). The difference was statistically significant (P < P <0.05). Conclusion The local injection of epinephrine on the duodenal papilla before the end of ERCP can effectively prevent the occurrence of post-operative pancreatitis and hyper-amylase.