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随着化疗在多种肿瘤的广泛应用,已有数篇文章提出脑转移的发病率正在增加的问题。某些病人由于应用细胞毒药物而存活较长时间,得以发现脑转移。脑转移最先见于急性白血病病人。在卵巢癌中也仅见于Mayer等人的文章中。他们在576例卵巢癌的尸检病例中发现5例脑转移,在1,441例其他癌瘤脑转移尸检病历中有14例起源于卵巢。Mayer等报告6例卵巢癌脑转移,4例为脑实质损害,2例累及脑膜。5例接受化疗,6例存活4年以上。作者自1969～1979年共收治430例卵巢癌患者,5例证实有脑转移。例1、64岁,1968年2月行全子宫及双附件切除
With the widespread use of chemotherapy in a variety of tumors, several articles have raised the issue of the increasing incidence of brain metastases. Some patients have been brain-transplanted for longer periods of time due to the use of cytotoxic drugs. Brain metastasis first seen in acute leukemia patients. Also found in Mayer et al. In ovarian cancer. They found 5 cases of brain metastases in autopsy cases of 576 ovarian cancers and 14 of 1441 cases of metastatic autopsy history in 1,441 other cancers originated in the ovary. Mayer et al reported 6 cases of brain metastases of ovarian cancer, 4 cases of brain parenchymal damage, 2 cases involving the meninges. 5 received chemotherapy and 6 survived more than 4 years. The authors treated 430 ovarian cancer patients from 1969 to 1979 and confirmed brain metastases in 5 patients. Cases of 1,64 years old, in February 1968 the line of hysterectomy and double attachment resection