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肿瘤坏死因子（Ｔｕｍｏｒｎｅｃｒｏｓｉｓｆａｃｔｏｒ，ＴＮＦ）是机体炎症与免疫反应的重要调节因子。本文取肾小球疾病患者晨尿５８份进行ＴＮＦ检测。结果表明，肾小球疾病患者尿中ＴＮＦ值明显高于正常对照，差别有显著性。肾小球肾炎、肾病综合征及紫癜肾炎分别与正常对照比较，ＴＮＦ值明显高于正常对照，差别有显著性。而肾小球肾炎、肾病综合征及紫癜肾炎进行两两比较，差异无显著性。山此建议将尿中检测到ＴＮＦ做为肾小球受损的一项指标，协助诊断肾小球疾病。
Tumor necrosis factor (TNF) is an important regulator of inflammation and immune response in the body. In this paper, 58 patients with glomerular disease morning urine for TNF detection. The results showed that patients with glomerular disease urinary TNF was significantly higher than the normal control, the difference was significant. Glomerulonephritis, nephrotic syndrome and purpura nephritis, respectively, compared with the normal control, TNF was significantly higher than the normal control, the difference was significant. The glomerular nephritis, nephrotic syndrome and purpura nephritis for any comparison, no significant difference. Hill This proposed urinary TNF detected as an indicator of glomerular damage, to help diagnose glomerular disease.