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HGF是一种肝细胞特有的血小板衍生物,是在1984年Nakamura等人从切除了部分肝脏的大鼠的血小板中提取出来的,因此被命名为肝细胞生长因子(hepatocyte growth factor,HGF)。该因子是一种多功能细胞活性因子,具有很强的促有丝分裂的作用,可以诱导上皮细胞和成纤维细胞发生细胞离散
HGF, a hepatocyte-specific platelet derivative, was extracted in 1984 by Nakamura et al. From platelet-excised rat livers and was therefore named hepatocyte growth factor (HGF). This factor is a multi-functional cellular activity factor that has a strong mitogenic effect and can induce cell dispersion in epithelial cells and fibroblasts