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综述了钩藤总碱、钩藤碱和异钩藤碱对心血管系统和神经系统等方面的药理作用,包括降低血压、减慢心率、抗心律失常、脑缺血保护,以及镇静等作用,其作用机制与钙通道阻滞、钾通道开放、以及神经递质转运和代谢的调节有关。
The pharmacological effects of rhynchophylline, rhynchophylline and isorhynchophylline on the cardiovascular system and nervous system were reviewed, including the effects of lowering blood pressure, slowing heart rate, anti-arrhythmia, cerebral ischemia protection, and sedation. Its mechanism of action is related to the blockage of calcium channels, the opening of potassium channels, and the regulation of neurotransmitter transport and metabolism.