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目的探讨热性惊厥患儿血清电解质和血糖的变化及其临床意义。方法选取2009年6月-2010年12月儿科住院的呼吸道感染并发热性惊厥患儿38例和呼吸道感染无惊厥患儿42例,分别作为观察组和对照组,测定和比较两组患儿血清电解质和血糖值。结果观察组血清钠离子浓度为(133.05±1.74)mmol/L、氯离子浓度为(100.37±1.79)mmol/L;对照组血清钠离子浓度为(142.19±1.85)mmol/L、氯离子浓度为(104.57±1.55)mmol/L,差异均有统计学意义(P<0.01);观察组和对照组血糖浓度依次为(6.93±0.87)、(5.12±0.55)mmol/L,差异有统计学意义(P<0.01)。观察组在治疗后的血清钠离子、氯离子浓度分别为(140.89±2.68)、(103.29±1.94)mmol/L,均高于发生惊厥时的浓度(P<0.01);观察组在治疗后的血糖浓度为(5.31±0.68)mmol/L,明显低于发生惊厥时,差异有统计学意义(P<0.01)。结论婴幼儿发生热性惊厥时存在血钠、血氯水平降低和血糖升高,在热性惊厥患儿的治疗中应纠正血钠水平和高血糖。
Objective To investigate the changes of serum electrolytes and blood glucose in children with febrile seizures and its clinical significance. Methods From June 2009 to December 2010, 38 pediatric patients with respiratory tract infection and febrile seizures and 42 children with respiratory tract infection without convulsion were selected as the observation group and the control group respectively. The serums of the two groups were measured and compared Electrolytes and blood glucose levels. Results Serum sodium concentration in the observation group was (133.05 ± 1.74) mmol / L and the chloride ion concentration was (100.37 ± 1.79) mmol / L. The serum sodium concentration in the control group was (142.19 ± 1.85) mmol / L and the chloride ion concentration (104.57 ± 1.55) mmol / L, the difference was statistically significant (P <0.01). The blood glucose levels in the observation group and the control group were (6.93 ± 0.87) and (5.12 ± 0.55) mmol / L, (P <0.01). The levels of serum sodium and chloride in the observation group were (140.89 ± 2.68) and (103.29 ± 1.94) mmol / L, respectively, which were higher than those in the control group (P <0.01) The blood glucose level was (5.31 ± 0.68) mmol / L, which was significantly lower than that of convulsions (P <0.01). Conclusions Infants with febrile seizures present with hyponatremia, decreased blood levels of blood chlorine and elevated blood glucose levels, and should be able to correct the serum sodium level and hyperglycemia in the treatment of children with febrile seizures.