目的:观察α-细辛脑治疗小儿毛细支气管炎临床疗效与安全性。方法:70例符合入组标准的小儿毛细支气管炎患者随机分为观察组和对照组各35例,对照组进行常规综合治疗,观察组在对照组基础上静滴α-细辛脑注射液,两组均治疗7d,观察患儿症状、体征改善情况及改善时间,评价两组临床疗效,同时记录不良反应发生情况。结果:观察组治愈率、总有效率明显高于对照组(P<0.01)。观察组咳嗽、喘憋、肺部哮鸣音、痰鸣音、湿哆音等症状消失时间明显短于对照组(P<0.01)。结论:α-细辛脑能够有效缓解毛细支气管炎患儿的不适症状,缩短住院时间,提高临床疗效。 Objective: To observe the clinical efficacy and safety of α-Asarone in children with bronchiolitis. Methods: A total of 70 children with bronchiolitis were enrolled in this study. The patients in the observation group and the control group were randomly divided into observation group (35 cases) and control group (35 cases). The control group was treated with conventional therapy. The observation group was given α-Asarone Injection on the basis of the control group, The two groups were treated for 7 days, the symptoms and signs of children were observed and the improvement time was observed. The clinical efficacy of the two groups were evaluated, and the incidence of adverse reactions was recorded. Results: The cure rate and total effective rate in the observation group were significantly higher than those in the control group (P <0.01). Observation group cough, wheezing, lung wheeze, phlegm, wet dumbbells and other symptoms disappeared significantly shorter than the control group (P <0.01). Conclusion: Asarone can effectively relieve the symptoms of children with bronchiolitis, shorten the length of hospital stay and improve the clinical curative effect.