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①目的观察复发性口腔溃疡（ＲＯＵ）病人血清甲状腺激素含量的动态变化，以探讨ＲＯＵ与正常甲状腺功能病态综合征（ＥＳＳ）的关系。②方法应用放射免疫分析法对７０例ＲＯＵ病人的初发期、溃疡期、愈合期及间歇期和６０例对照组血清ＦＴ４，ＦＴ３，ｒＴ３和ＴＳＨ含量进行测定。③结果ＲＯＵ病人各期血清ＦＴ４，ＦＴ３含量均低于对照组（ｔ＝２．１８６～１１．７５８，Ｐ＜０．０５，０．００１）；病人初发期血清ｒＴ３含量高于对照组（ｔ＝２．６５７，Ｐ＜０．０１），其他各期病人血清ｒＴ３和所有病期病人血清ＴＳＨ含量与对照组比较，差异无显著意义（ｔ＝０．５３３～１．５７４，Ｐ均＞０．０５）。④结论ＲＯＵ病人存在ＥＳＳ，且属于低Ｔ３低Ｔ４型。
Objective To observe the dynamic changes of serum thyroid hormones in patients with recurrent oral ulcer (ROU) so as to investigate the relationship between ROU and normal thyroid dysfunction syndrome (ESS). Methods The serum levels of FT4, FT3, rT3 and TSH in 70 cases of ROU were detected by radioimmunoassay in the initial stage, the ulcer stage, healing and intermission, and 60 cases of control group. Results The levels of serum FT4 and FT3 in each stage of patients with ROU were lower than those in the control group (t = 2.186-11.758, P <0.05, 0.001) t = 2.657, P <0.01). There was no significant difference in the levels of serum rT3 and serum TSH among all the other stages (t = 0.533-1.574, P> 0.05). ④ Conclusion ROU patients with ESS, and belong to low T3 low T4 type.