论文部分内容阅读
扩张型心肌病(DCM)是一种常见疾病,主要表现为一侧或双侧心腔扩大、心肌收缩期功能减退、伴或不伴有充血性心力衰竭。其中约35%的DCM为家族性DCM(FDC)。目前对FDC尚无特殊有效的治疗方法,近年来研究者们在FDC治疗的实验室研究中,分别采用基因治疗、细胞移植的手段治疗DCM大鼠,取得了一定的效果,同时,基因结合细胞治疗FDC也为研究者所关注,本文就此三方面作一综述。
Dilated cardiomyopathy (DCM) is a common disease that is characterized by enlargement of one or both chambers of the heart, diminished cardiac systolic dysfunction with or without congestive heart failure. About 35% of DCM is familial DCM (FDC). At present, there is no specific and effective treatment for FDC. In recent years, researchers in the laboratory study of FDC treated gene therapy and cell transplantation to treat DCM rats, and achieved some results. At the same time, gene-bound cells The treatment of FDC is also of concern to researchers, this article reviews the three aspects.