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１９９３～１９９４年应用日本国立卫生研究所研制的明胶颗粒凝集试验（ＰＡ）对我国ＤＰＴ的诊断方法进行了研究，同时对人群ＤＰＴ的抗体水平进行了监测。此次调查１９９３年采血９００人份，１９９４年采血３００人份，结果表明ＰＡ法使用方便，结果稳定，易于观察，可弥补我国被动血凝试验（ＰＨＡ）存在的缺陷，检测白喉和破伤风与国内ＰＨＡ法有较好的相关性，但ＰＨＡ法似更敏感，检测百日咳ＰＡ法与国内微量凝集试验（ＭＡ）相关性较差，ＭＡ法较ＰＡ法敏感得多。人群ＤＰＴ抗体水平检测结果表明，人群抗体水平不是很高，分别为百日咳阳性率为９５．０％，≥１：３２０的为４．７％，ＧＭＴ为１：１２１；白喉阳性率为６２．９％，ＧＭＴ为０．０２８０ＩＵ／ｍｌ；１９９３年破伤风阳性率为７０．５％，ＧＭＴ为０．１４１０ＩＵ／ｍｌ；１９９４年破伤风阳性率为７５．７％，ＧＭＴ为０．３２８１ＩＵ／ｍｌ，提示应重视加强基础免疫和强化免疫。调查结果还显示，抗体水平城市高于农村，并随年龄增高而下降，大年龄组抗体水平较低，造成目前大年龄组发病较高。
From 1993 to 1994, the method of gelatin particle agglutination test (PA) developed by Japan National Institute of Health was used to study the diagnostic method of DPT in our country. At the same time, the antibody level of DPT in the population was monitored. The survey collected 900 blood samples in 1993 and 300 blood samples in 1994. The results showed that the PA method is easy to use, the results are stable and easy to observe. It can make up for the shortcoming of our country’s passive coagulation test (PHA) The domestic PHA method has a good correlation, but the PHA method is more sensitive, the detection pertussis PA method and domestic micro agglutination test (MA) correlation is poor, MA method is much more sensitive than the PA method. The level of DPT antibody in human population showed that the population antibody level was not very high, the positive rate of pertussis was 95.0%, the rate of ≥1: 320 was 4.7%, the GMT was 1: 121 and the positive rate of diphtheria was 62.9 %, GMT 0.0280IU / ml; 1993 tetanus positive rate was 70.5%, GMT was 0.1410IU / ml; 1994 tetanus positive rate was 75.7%, GMT was 0.3281IU / ml, Prompt attention should be paid to strengthen basic and intensive immunization. The survey also showed that the antibody level in urban areas was higher than that in rural areas and decreased with increasing age, and the antibody levels in older age groups were lower, resulting in a higher incidence in the current large age group.