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近几年对肾胚瘤患儿的治疗有很显著的进步,治疗效果的提高很大程度是由于合理地使用了抗肿瘤药物。长春新硷、放线菌素D、链黑霉素及环磷酰胺对治疗肾胚瘤的复发和转移有很好的效果。作者报导了21例不能手术的肾胚瘤患儿联合使用这些药物的结果。所有患儿肿瘤体积都较大,直径15～25厘米,其中3例有肺内多发转移;都有周身中毒症状,大部分患儿几乎卧床不起。由于肿瘤体积大或患儿周身状态不佳,入院当时不能手术或手术有危险。
In recent years, there is a significant improvement in the treatment of children with nephroblastic tumors. The improvement of the therapeutic effect is largely due to the rational use of anti-tumor drugs. Vincristine, actinomycin D, streptozotocin and cyclophosphamide for the treatment of neoplasia recurrence and metastasis have a good effect. The authors report the results of a combination of these drugs in 21 patients with unresectable nephroblastoma. All children with larger tumor sizes, diameter 15 ~ 25 cm, of which 3 cases of multiple lung metastases; have symptoms of whole body poisoning, most children almost bedridden. Because of the large tumor size or poor condition of the child’s body, admitted to the hospital was not surgery or surgery at risk.