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为分析严重急性呼吸综合征(SARS)病人血清肌酸激酶心肌型同工酶(CKMB)的变化,用以发现早期急性心肌损伤,将204名SARS病人按年龄分为7组,选出每人住院期间测得的CKMB最高值,计算每组CKMB异常患者的百分率及每组CKMB的平均值及标准差(x±s),并进行统计学分析。再将204名病人按CKMB是否正常分为2组,统计每组中多个肺叶病变患者的比例。结果CKMB异常的百分率20岁以下组28%,21～30岁组12%,31～40岁组17%,41～50岁组22%,51～60岁组42%,61～70岁组33%,大于70岁组26%;CKMB值按上述顺序依次为(23±11)、(19±16)、(21±15)、(20±10)、(24±15)、(36±26)、(22±11)IU/L。CKMB异常组中多个肺叶病变患者占53%,CKMB正常组为35%。提示部分SARS病人存在急性心肌损害,出现CKMB异常的百分比最高的年龄组为51～60岁组;CKMB平均值最高的年龄组为61～70岁组;CKMB异常组中多个肺叶病变患者明显高于CKMB正常组。
To analyze changes in serum creatine kinase Myocardial Isozyme (CKMB) in patients with Severe Acute Respiratory Syndrome (SARS) for the detection of early acute myocardial injury, 204 SARS patients were divided into 7 groups by age, selected for each The highest CKMB values measured during hospitalization, the percentage of abnormal CKMB patients in each group and the mean and standard deviation (x ± s) of CKMB in each group were calculated and statistically analyzed. 204 patients were divided into two groups according to whether CKMB was normal or not, then the proportion of patients with multiple lobular lesions in each group was counted. Results The percentage of abnormalities in CKMB was 28% in the group of under 20, 12% in 21-30, 17% in 31-40, 22% in 41-50, 42% in 51-60, %, And 26% higher than the 70-year-old group. The CKMB values were (23 ± 11), (19 ± 16), (21 ± 15), (20 ± 10), (24 ± 15) and ), (22 ± 11) IU / L. Among the CKMB abnormalities group, 53% were in multiple lobular lesions and 35% in CKMB normal group. The results showed that there were acute myocardial damage in some SARS patients, the age group with the highest percentage of CKMB abnormalities was 51-60 years old group, the highest average age group of CKMB was 61-70 years old group, multiple lung disease group was significantly higher in CKMB abnormal group CKMB normal group.