未破裂卵泡黄素化综合征(Luteinized unruptured follicle syndrome)简化为LUFS。是指月经周期规则,并假设有排卵,但实际月经中期卵泡未破裂、无排卵的一组征候群。它是引起不明原因不孕的重原因之一。近年来,国外学者对此作了很多研究,对其病机、诊断及处理虽有一定见解,但在某些方面尚有争论。一、正常月经周期中排卵的过程正常月经周期中的早期滤泡期,卵巢内可以同时有几个滤泡发育,但有一个滤泡由于其微环境条件可成为优势滤泡。优势滤泡内芳香化酶作用较强产生较 Unruptured follicle luteinized syndrome (Luteinized unruptured follicle syndrome) reduced to LUFS. Refers to the rules of the menstrual cycle, and assuming ovulation, but the actual mid-term follicles are not ruptured, anovulatory symptoms of a group. It is one of the reasons that causes unexplained infertility. In recent years, many foreign scholars made a lot of research on this, although there is some insight into their pathogenesis, diagnosis and treatment, but there are still some controversies in some aspects. First, the normal menstrual cycle in the process of ovulation Normal menstrual cycle in the early follicular phase, ovarian follicular development can have several at the same time, but there is a follicle because of its micro-environmental conditions can become the dominant follicles. Aroma follicles within the strong role of aromatase produced more