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近年来研究证明,用人脑胶质瘤的纯净瘤组织提取的碱性蛋白(GBP)具有共同抗原的特性,用GBP 作为抗原,从免疫动物肝脾及淋巴组织中提取的免疫核糖核酸(iRNA),可应用于各种恶性肿瘤的辅助治疗,从而提高机体的免疫功能,达到抑制肿瘤生长的目的。本院从1983年开始,应用本院制取的人脑胶质瘤碱性蛋白免疫核糖核酸,治疗恶性脑瘤3例,临床观察效果尚满意。一、免疫核糖核酸的制取从手术切除人脑胶质细胞瘤的纯净瘤组织中提取GBP,免疫动物(绵羊),待其产生细胞免疫及体液免疫反应后,将已免疫致敏的绵羊放血致死,取其肝脾和
In recent years, it has been proved that the basic protein (GBP) extracted from the pure tumor tissue of human glioma has the common antigenic characteristic, and the immunological ribonucleic acid (iRNA) extracted from the liver, spleen and lymphoid tissues of the immunized animals using GBP as an antigen, , Which can be used in the adjuvant treatment of various malignancies to improve the body’s immune function and achieve the purpose of inhibiting tumor growth. Our hospital since 1983, the application of our hospital system of human glioma alkaline protein immunosuppressive nucleic acid, the treatment of malignant brain tumor in 3 cases, the clinical observation results are still satisfactory. First, the preparation of immunological ribonucleic acid extracted from purely surgical resection of human glioblastoma GBP, immunized animals (sheep) until the occurrence of cellular and humoral immune response, the immune-sensitized sheep bleeding To death, take the liver and spleen and