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小鼠、大鼠、豚鼠和地鼠经滴鼻和腹腔接种淋巴细胞性脉络丛脑膜炎病毒（ＬＣＭＶ），一月后测抗体效价。发现小鼠经滴鼻和腹腔接种ＬＣＭＶ均有高效价抗体产生（１：１０２４０）；大鼠经滴鼻和腹腔接种均无明显可测抗体；豚鼠腹腔接种ＬＣＭＶ易至发病，幸存者（２／５）产生高效价抗体；地鼠经滴鼻和腹腔接种ＬＣＭＶ均易致发病和死亡。
Mice, rats, guinea pigs and hamsters were intranasally and intraperitoneally vaccinated with lymphocytic choriomeningitis virus (LCMV). Antibody titers were measured after one month. (1: 10240). There was no measurable antibody in intranasal and intraperitoneal inoculation in rats. LCMV was easy to be induced in guinea pig peritoneal inoculation. Survivors (2 / 5) produce high titer antibodies; hamsters intranasal and intraperitoneal LCMV are easy to cause morbidity and mortality.