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患多毛症的妇女,其面部、口唇周围、两手臂和小腿等部位的毳毛增多,增粗、眉毛、腋毛和阴毛也变得浓密。该病是由于卵巢产生雄激素过多,或者毛囊中的雄激素受体对雄激素刺激敏感所致。安体舒通在临床上是用于利尿或治疗轻型高血压的。但最近发现,安体舒通还有抗雄激素的作用,它既能抑制卵巢产生雄激素。又可以通过毛囊中的雄激素受体抑制卵巢
Women suffering from hirsutism, the face, lips, arms and legs and other parts of the beard hair increased, thickening, eyebrows, armpit hair and pubic hair has become thick. The disease is due to ovarian hyperandrogenism, or androgen receptor in the hair follicle is sensitive to androgen stimulation. Spironolactone is clinically used for diuretic or light-induced hypertension. However, it has recently been found that spironolactone also has an anti-androgenic effect that inhibits ovarian production of androgens. Ovarian can also be inhibited by the androgen receptor in hair follicles