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细胞角蛋白 (cytokeratin,CK)分为两型： CK1～ 8为 Ⅱ 型 ,CK9～ 20为Ⅰ 型 ,两型成员常成对参与各种上皮细胞中间纤维丝的构成。 CK8/CK18为最小的一对 ,与组织多肽抗原 (tissue polypeptide antigen,TPA)和肿瘤发展相关， TPA已被作为一种较广谱肿瘤标志物 [1]。我们试制酶?
Cytokeratin (CK) is divided into two types: CK1～8 is type II, CK9～20 is type I. Both types of members often participate in the formation of intermediate filaments in various epithelial cells. CK8/CK18 is the smallest pair, associated with tissue polypeptide antigen (TPA) and tumor development. TPA has been used as a broad-spectrum tumor marker [1]. We try to make enzymes?