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对２００ 对自然流产夫妇和２００ 对已生育正常胎儿并无自然流产史的夫妇的外周血染色体随体联合频率（ＳＡＦ） ，进行分析研究。结果：ＳＡＦ流产组和对照组分别平均为３－６９％ 和２－６６ ％ ，两组比较差异有极显著意义（Ｐ＜ ０－０１） 。Ｄ／Ｇ 的分布频率流产组和对照组分别平均为０－４０ ±０－０１／ 细胞和０－３９ ±０－０１／ 细胞，两组比较差异无显著意义（Ｐ＞ ０．０５） 。流产组着丝点一核仁组织区融合（ＣｄＮＯＲ）频率平均为０－３４±０－１８／细胞，对照组平均为０－２４±０－１８／ 细胞，两组比较差异有显著意义（Ｐ＜ ０－０５） 。提示：自然流产夫妇ＳＡＦ和ＣｄＮＯＲ融合频率增高可能是造成自然流产的重要原因之一，对自然产夫妇的ＳＡＦ进行检测，具有临床意义。
Peripheral blood chromosomal association frequency (SAF) was analyzed in 200 pairs of spontaneous abortion couples and 200 couples with no history of spontaneous abortion. Results: SAF abortion group and control group averaged 3-69% and 2-66%, respectively, with significant difference between the two groups (P <0-01). The frequencies of D / G mismatch group and control group were 0-40 ± 0-01 / cell and 0-39 ± 0-01 / cell on average, respectively. There was no significant difference between the two groups (P> 0.05). The average frequency of CDNOR in the abortion group was 0-34 ± 0-18 / cell, while that in the control group was 0-24 ± 0-18 / cell, with significant difference between the two groups (P <0-05). Tip: spontaneous abortion couples SAF and Cd NOR fusion frequency may be caused by one of the important causes of spontaneous abortion, spontaneous abortion of the SAF test, with clinical significance.