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腹膜间皮细胞是腹腔最大的细胞群落 ,有着十分重要的生理功能。腹膜透析液具有生物不相容性 ,它通过pH值、缓冲剂、渗透压、葡萄糖及其降解产物等对间皮细胞及腹膜产生损害 ,从而影响腹腔局部防御功能并导致腹膜结构的改变。了解各种腹膜透析液生物不相容性的机理 ,对于改善透析液、保护长期透析时间皮细胞及腹膜功能具有十分重要的意义。
Peritoneal mesothelial cells are the largest intraperitoneal cell community, has a very important physiological function. Peritoneal dialysis fluid is biocompatible. It damages mesothelial cells and peritoneum by pH, buffer, osmotic pressure, glucose and its degradation products, and thus affects the peritoneal defensive function and changes in peritoneal structure. Understanding the mechanism of various kinds of peritoneal dialysis fluid biocompatibility is of great significance for improving the dialysate and protecting the skin cells and peritoneal function of the chronic dialysis time.