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目的:研究冠心病(CHD)患者的血脂、胆红素、血尿酸(UA)及纤维蛋白原(Fib)水平变化及临床意义。方法:选取2014年4月到2015年4月我院收治的CHD患者110例(研究组),另选取同期健康体检者110例(对照组),检测两组受检者血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、直接胆红素(DBIL)、间接胆红素(IBIL)、总胆固醇(TBIL)、UA以及Fib水平。结果:研究组TC、TG、LDL-C、UA以及Fib水平均显著高于对照组,两组比较差异具有统计学意义(P<0.05);研究组HDL-C、DBIL、IBIL以及TBIL均显著低于对照组,两组比较差异具有统计学意义(P<0.05)。结论:血脂水平异常,胆红素水平降低,UA以及Fib水平增高与CHD的发病有关。
Objective: To study the changes of serum lipids, bilirubin, serum uric acid (UA) and fibrinogen (Fib) in patients with coronary heart disease (CHD) and its clinical significance. Methods: A total of 110 CHD patients (study group) admitted to our hospital from April 2014 to April 2015 were enrolled. Another 110 healthy subjects (control group) were enrolled in this study. Serum total cholesterol (TC) TG, HDL-C, LDL-C, DBIL, IBIL, total cholesterol (TBIL) ), UA and Fib levels. Results: The levels of TC, TG, LDL-C, UA and Fib in the study group were significantly higher than those in the control group (P <0.05). The HDL-C, DBIL, IBIL and TBIL in the study group were significantly Lower than the control group, the difference between the two groups was statistically significant (P <0.05). Conclusion: Abnormal lipid levels, decreased bilirubin levels, elevated UA and Fib levels are associated with the incidence of CHD.