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化学名 2,4-二氟-α,α-双(1 H-1,2,4-三唑-1-基甲基)苯甲醇药效分类抗真菌药开发单位 (美国)辉瑞公司1978年上市厂商 (英)Pfizer Inc 1988年9月上市药理本品抗真菌作用在于抑制真菌细胞膜必要成分麦角甾醇合成酶,使麦角甾醇合成受阻,破坏了真菌细胞壁的完整性,从而影响真菌的生长、繁殖。体内外研究证实,本品对白色念珠菌、须发癣菌、犬小孢子菌、絮状表皮癣菌、鼠球孢子菌、荚膜组织胞浆菌、
Chemical name 2,4-difluoro-α, α-bis (1 H-1,2,4-triazol-1-ylmethyl) benzyl alcohol Pharmacodynamic Category Antifungal Drug Development Unit (USA) Pfizer 1978 Listed manufacturers (UK) Pfizer Inc listed in September 1988 Pharmacological The antifungal effect of this product is to inhibit the necessary components of the fungal cell membrane ergosterol synthase, ergosterol synthesis blocked, destroyed the integrity of the fungal cell wall, thus affecting fungal growth and reproduction . In vitro and in vivo studies have confirmed that the goods on Candida albicans, Trichophyton mentagrophytes, canis microsporum, Epidermophyton floccosum, coccidioidomycosis, Histoplasma capsulatum,