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目的:探讨用于诊断亚急性甲状腺炎(亚甲炎)的核医学检查方法的应用时机与价值。方法:对145例初诊亚甲炎的99mTc甲状腺γ显像结果进行总结,并与同期甲状腺131I摄取率(RAIU)、血清总三碘甲状腺原氨酸(TT3)、总甲状腺素(TT4)的关系进行对比分析;同时对27例的核医学随访结果进行分析。结果:145例亚甲炎初诊时甲状腺双叶弥漫性肿大多见,单叶肿大次之,单叶局部结节最少;其99mTc甲状腺γ显像结果全部异常。99mTc甲状腺γ显像结果与RAIU结果之间有良好的相关关系;与TT3、TT4水平增高之间有良好的负相关关系,但甲状腺肿大与99mTc甲状腺γ显像结果并非完全一致,不一致率为35.2%。结论:对初诊的亚甲炎病人应选99mTc甲状腺γ显像或RAIU作为确诊指标,同时测定TT3、TT4、甲状腺球蛋白抗体(TGA)、甲状腺微粒体抗体(TMA)水平;长期随访宜选择TT3、TT4、促甲状腺激素、TGA、TMA作为观察指标。
Objective: To explore the timing and value of the application of nuclear medicine for the diagnosis of subacute thyroiditis (methylene-actinitis). Methods: The results of 99mTc thyroid gland γ imaging in 145 cases of newly diagnosed metinitis were summarized and compared with the thyroid 131I uptake rate (RAIU), serum total triiodothyronine (TT3) and total thyroxine (TT4) For comparative analysis; at the same time, 27 cases of nuclear medicine follow-up results were analyzed. Results: 145 cases of first trimester meningitis diffuse thyroid diffuse more common, single follicles and the single leaflet local nodules the least; 99mTc thyroid gamma imaging results were all abnormal. 99mTc thyroid γ imaging results and RAIU results have a good correlation between; and TT3, TT4 levels have a good negative correlation between, but the thyroid gland and 99mTc thyroid gamma imaging results are not exactly the same, the inconsistency rate 35.2%. Conclusion: 99mTc thyroid γ imaging or RAIU should be selected as diagnostic criteria for newly diagnosed patients with mephitis, and the levels of TT3, TT4, TGA and TMA should be determined simultaneously. TT3 should be selected for long-term follow-up , TT4, thyrotropin, TGA, TMA as the observation index.