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作者报告用单克隆抗体流动血细胞计数技术定量检测109例未接受任何治疗的各种结缔组织病(CTD)患者外周血中T细胞及其免疫调节性T细胞亚群。本研究包括系统性红斑狼疮(SLE)41例,类风湿性关节炎(RA)23例,进行性系统硬化症(PSS)22例,原发性干燥综合征(SS)15例及混合结缔组织病(MCTD)8例。因为T细胞亚群可随着年龄、性别的不同而有所改变,所以同时配对检查与患者年龄、性别相同的健康者作为对照。
The authors report the use of monoclonal antibody flow cytometry to quantify T lymphocytes and their immunoregulatory T-cell subsets in peripheral blood from 109 patients with various connective tissue disease (CTD) who have not undergone any treatment. This study included 41 cases of systemic lupus erythematosus (SLE), 23 cases of rheumatoid arthritis (RA), 22 cases of progressive systemic sclerosis (PSS), 15 cases of primary Sjogren’s syndrome (SS) and mixed connective tissue Disease (MCTD) in 8 cases. Because T-cell subsets vary with age and gender, paired-ups are also used as controls for patients with the same age and gender.