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鹤草酚是我国新近发现的有效驱绦药,本文探讨了鹤草酚驱杀肝片吸虫的新应用。于38℃下休外温孵实验证明,10~(-3), 10~(-4), 5×10~(-5), 10~(-5)鹤草酚亚枫注射液杀死牛肝片吸虫平均时间分别为5.6,16.2,32.6,67.6分钟,该虫在生理盐水中100分钟一直存活。用25只肝片吸虫病患羊,其中5只给予已知有效药物对照,其余18只羊肌注鹤草酚亚矾注射液后进行剖析,结果给鹤草酚的羊有15只已将肝片吸虫全部驱净,3只羊仅剩1-2条虫(正常患病羊平均有虫28条以上)。用14只患羊秋季预防治疗一次,结果发病仅2只,有效率85.7%。用4i只患羊在发病时期用该药治疗,治愈率85.1%。对7头您牛在发病期间用该药治疗,均获全愈。证明鹤草酚对肝吸虫具有较强的杀灭作用,对牛羊肝片吸虫病有较好的驱I住治疗作用。对人肝吸虫病尚未进行临床,本研究为治疗人肝吸虫病提供一定的实验基础。
The herbicide phenol is an effective antidose drug recently discovered in China. This article discusses the new application of anti-herbicide to repel liver flukes. The incubation experiment at 38°C showed that 10~(-3), 10~(4), 5*10~(-5), 10~(5) agrimonol saxone injection killed the cattle. The average time for Fasciola hepatica was 5.6, 16.2, 32.6, and 67.6 minutes, respectively, and the worm remained alive in physiological saline for 100 minutes. With 25 sheep suffering from hepatic schistosomiasis, 5 of them were given a known effective drug control, and the remaining 18 goats were intramuscularly injected with agrimony and subtilisin. All fluke worms were driven away, leaving only 1-2 worms in 3 sheep (average worms averaged 28 or more). With 14 sheep suffering from fall prevention and treatment in autumn, the incidence was only 2 and the effective rate was 85.7%. With 4i only suffering from sheep during the onset of treatment with this drug, the cure rate was 85.1%. Treatment of seven cows with this drug during the onset of the disease was fully recovered. It is proved that the anticoagulant has a strong killing effect on the liver flukes, and it has a good therapeutic effect on the liver flukes. Human liver flukes have not yet been clinically studied. This study provides a certain experimental basis for the treatment of human liver flukes.