新生儿先天性畸形46例,占同期产科接生的新生儿总数的13.01‰(46/3535)。其中低体重儿18例(39.1％),早产儿17例(37.0％),死胎死产儿21例(45.6％)。其父母近亲婚配者5例,家族中有畸形者7例;初产妇发生率为9.67‰,经产妇为23.6‰。(P<0.01);妊娠早期有可疑致畸诱因者31例(67.4％),出生季节以夏秋季居多。 46 cases of congenital malformations of newborns, accounting for 13.01 ‰ (46/3535) of the total number of newborns receiving obstetric delivery during the same period. There were 18 cases (39.1%) with low birth weight, 17 cases (37.0%) with premature birth and 21 (45.6%) stillbirths. The parents of their relatives in 5 cases of marriage, deformities in the family of 7 cases; primipara was 9.67 ‰, the maternal was 23.6 ‰. (P <0.01). There were 31 cases (67.4%) of suspicious teratogenic factors in early gestation, most of them were in summer and autumn.