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本文介绍4例全身性红斑狼疮(SLE)与淋巴瘤继发产生的自然病史和治疗。病史摘要见下表。讨论:作者观察的12例SLE继发淋巴瘤的病人均为女性。首次出现SLE症状平均年龄36岁,发生淋巴瘤平均年龄46岁。SLE先于淋巴瘤2月至12年。有许多迹象表明SLE病人继发发生淋巴瘤可能是由于免疫缺乏。先天性免疫缺乏的病人恶性肿瘤的发病率比予期的要大1万倍,淋巴瘤占其中很高的比例。NZB品系鼠自发产生SLE样病伴肾小球肾炎,抗核因子、LE细胞阳性,淋巴瘤的发病率也很高。SLE病人迟发过敏反应不良,T细胞B细胞功能减弱。现代医学观点支持SLE的原发损害是由于T细
This article describes four cases of systemic history of lupus erythematosus (SLE) and lymphoma secondary to the history and treatment. The history is summarized in the following table. Discussion: The authors observed that all 12 patients with SLE secondary lymphoma were female. The first appearance of SLE symptoms average age 36 years, the average age of lymphoma occurred 46 years old. SLE precedes lymphomas from February to 12 years. There are many indications that lymphoma secondary to SLE may be due to immunodeficiency. The incidence of malignant tumors in patients with congenital immunodeficiency is 10,000 times greater than expected, with lymphoma accounting for a high proportion. NZB strains of spontaneous SLE-like disease associated with glomerulonephritis, anti-nuclear factor, LE cells were positive, the incidence of lymphoma is also high. SLE patients with delayed acute allergic reaction, T cell B cell function weakened. Modern medicine point of view to support the primary damage SLE is due to T fine