N-烷基化的间氨基苯酚(MAP)产物作为重要的有机原料和医药中间体,广泛应用于石油化学工业、农药、医药、印染等行业。间氨基苯酚的应用依赖于氮上的烷基化反应,芳胺的N-烷基化反应在在医药、染料、石油化工等许多领域也具有广泛应用,合成方法众多。本文主要介绍了间氨基苯酚的合成方法和其N-烷基化反应的研究进展。 N-alkylated m-aminophenol (MAP) products are widely used in petrochemical industry, pesticide, medicine, printing and dyeing industries as important organic raw materials and pharmaceutical intermediates. The application of m-aminophenol relies on the alkylation of nitrogen. The N-alkylation of aromatic amines is also widely used in many fields such as medicine, dyes, petrochemicals and many other synthetic methods. This article mainly introduced the synthesis of m-aminophenol and its N-alkylation reaction.