眼部新生血管性疾病是损害人类视力的主要疾病,其发病机制非常复杂,目前认为眼内新生血管形成依赖于血管生长促进因子及抑制因子之间的消长平衡。近年来,内源性血管形成抑制剂在眼部新生血管性疾病中的作用越来越受到关注,本文就与眼内新生血管形成有关的内源性血管形成抑制剂作简要综述。 Ocular neovascularization is a major disease that damages human vision. Its pathogenesis is very complicated. It is currently believed that intraocular neovascularization depends on the balance between the growth promoting factor and inhibitory factor. In recent years, the role of endogenous angiogenesis inhibitors in ocular neovascular diseases has drawn increasing attention. In this review, we briefly reviewed endogenous angiogenesis inhibitors associated with ocular neovascularization.