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目的:探讨尿路感染患者行加替沙星联合呋喃妥因治疗的临床效果与其安全性。方法:将60例尿路感染患者随机分为对照组与观察组,对照组行加替沙星治疗,观察组在此基础上施加呋喃妥因治疗,对比两组患者的治疗总有效率、细菌清除率以及不良反应发生率。结果:两组经治疗后,观察组的治疗总有效率以90.0%明显高于对照组的70.0%;细菌清除率以93.3%明显高于对照组的73.3%,组间比较差异显著(P<0.05)。两组均未见严重不良反应。结论:尿路感染患者行加替沙星联合呋喃妥因治疗的效果显著,值得推广。
Objective: To investigate the clinical effect and safety of gatifloxacin plus nitrofurantoin in patients with urinary tract infection. Methods: Sixty patients with urinary tract infection were randomly divided into control group and observation group. The control group was treated with gatifloxacin. The observation group was treated with nitrofurantoin. The total effective rate and bacterial clearance rate As well as the incidence of adverse reactions. Results: After treatment, the total effective rate in the observation group was significantly higher than that in the control group (90.0% vs. 70.0%); the bacterial clearance rate was 93.3% in the observation group significantly higher than that in the control group (73.3%) (P < 0.05). No serious adverse reactions were seen in both groups. Conclusion: The effect of gatifloxacin combined with nitrofurantoin in patients with urinary tract infection is significant and worthy of promotion.