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[目的]探讨异型淋巴细胞在轮状病毒(RV)肠炎中的变化及临床意义。[方法]对356例RV肠炎患儿的外周血涂片分类计数异型淋巴细胞数量,同时进行分型,并与50例健康儿童进行比较。[结果]356例中有351例(98.6%)检出异型淋巴细胞(异淋),92例异淋数量≥10%以上者分型,以单核细胞型和浆细胞型为主,未见原始细胞型。[结论]RV感染患儿的外周血中可以出现数量不等的异淋,是判断病毒感染的快速、敏感、准确的指标应重视人工涂片,观察血细胞形态。
[Objective] To investigate the changes and clinical significance of atypical lymphocytes in rotavirus (RV) enteritis. [Method] The numbers of atypical lymphocytes in 356 cases of RV enteritis were classified and counted at the same time, and compared with 50 healthy children. [Results] There were 351 cases (98.6%) out of the 356 cases were detected abnormal lymphocytes (leaching lymphocytes), 92 cases of heterophylla ≥ 10% were typed to monocyte type and plasma cell type, no Prototype. [Conclusion] The number of peripheral blood in children with RV infection may vary from one to another. It is a fast, sensitive and accurate indicator to judge the virus infection. Artificial smears should be taken into account to observe the morphology of blood cells.