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在系统性红斑狼疮(SLE)众多的自身抗体中,以抗天然(双链)脱氧核糖核酸抗体(AnDA)最令人瞩目。对于SLE,AnDA不单具有较高的特异性,而且其免疫复合物所诱发的第Ⅲ型变态反应又是SLE系统性损伤的主要原因,在诊断治疗及预后上均有意义,成为风湿性疾病必不可少的临床检测项目之一。
Of the many autoantibodies in systemic lupus erythematosus (SLE), the most striking is the anti-native (double-stranded) DNA antibody (AnDA). For SLE, AnDA not only has a high specificity, but also immune complex induced type Ⅲ allergic reaction is the main reason for SLE systemic injury, both in the diagnosis and treatment and prognosis of a sense of rheumatic diseases will be One of the essential clinical testing items.