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目的 :从更年期发病相关因素角度 ,探索中药复方宁神合剂治疗更年期综合征的作用机理 ,以免疫系统为重点 ,为以后进一步研究提供良好基础。方法 :通过去卵巢手术造模 ,以更年安为对照 ,分宁神合剂大、中、小剂量组 ,观察各组大鼠IL -2的变化。结果 :宁神合剂能改善去卵巢大鼠IL -2的数值 ,有效调节去卵巢大鼠免疫功能 ,可能为宁神合剂临床疗效作用的机理之一
Objective : To explore the mechanism of the treatment of climacteric syndrome with Chinese herbal compound Ningshen mixture from the perspective of the related factors of menopausal morbidity, focusing on the immune system and providing a good basis for further research. Methods :The model of ovariectomy was used to compare the changes of IL-2 in the rats of the group with large, medium, and small doses of Ningshen Mixture. Results : Ningshen Mixture can improve the value of IL-2 in ovariectomized rats and effectively regulate the immune function of ovariectomized rats. It may be one of the mechanisms of the therapeutic effect of Ningshen Mixture.