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应用放射免疫分析法,对40例早产儿血清中三碘甲腺原氨酸(T3)、甲状腺素(T4)和促甲状腺激素(TSH)含量进行观察。结果显示早产儿血清中L3、L4及TSH含量均显著低于健康足月儿(P值分别<0.01、<0.01和<0.05);临床观察发现,40例早产儿中,出现体温不升者33例,不同程度硬肿者37例,经口服甲状腺片治疗后,上述症状有不同程度的改善,平均住院天数显著低于同期对照组(P<0.05)。提示早产儿存在暂时性低甲状腺素血症,临床应用甲状腺激素有治疗价值。
The content of triiodothyronine (T3), thyroxine (T4) and thyrotropin (TSH) in serum of 40 premature infants were observed by radioimmunoassay. The results showed that serum levels of L3, L4 and TSH in preterm infants were significantly lower than healthy full-term infants (P <0.01, <0.01 and <0.05, respectively) There were 33 patients with ascending body temperature and 37 patients with different degrees of edema. After oral administration of thyroid tablets, the above symptoms were improved to some extent, the average length of stay was significantly lower than that of the control group at the same period (P <0.05). Prompted the existence of temporary hypothyroxinemia in preterm children, clinical application of thyroid hormone has therapeutic value.