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目的:探讨原发性高血压患者肾动脉阻力指数(renal resistive index,RRI)与超敏C反应蛋白(high-sensitiveC-reactive protein,hs-CRP)的相关性。方法:原发性高血压患者82例,应用彩色多普勒超声测量RRI,据RRI分为A组(RRI≥0.7,n=34)和B组(RRI<0.7,n=48),彩超检查当天测量收缩压(SBP)、舒张压(DBP),计算脉压(PP)、平均血压(MBP),检测肌酐、尿素氮等生化指标,免疫比浊法测hs-CRP,分析两组间各指标的差异。结果:A组年龄、PP、SBP及hs-CRP水平都明显高于B组(均P<0.01),直线相关分析显示,RRI同hs-CRP呈正相关(P<0.01)。结论:原发性高血压患者RRI与hs-CRP水平相关。
Objective: To investigate the relationship between renal resistive index (RRI) and high-sensitive C-reactive protein (hs-CRP) in patients with essential hypertension. Methods: Eighty-two patients with essential hypertension were enrolled in this study. Color Doppler echocardiography was used to measure RRI. According to RRI, group A (RRI ≥ 0.7, n = 34) and group B (RRI <0.7, n = 48) The SBP, DBP, PP and MBP were measured on the same day. The biochemical indexes such as creatinine and urea nitrogen were measured. The hs-CRP was measured by immunonephelometry. Differences in indicators. Results: The age, PP, SBP and hs-CRP levels in group A were significantly higher than those in group B (all P <0.01). The linear correlation analysis showed that there was a positive correlation between RRI and hs-CRP (P <0.01). Conclusion: RRI is associated with hs-CRP in patients with essential hypertension.