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喀麦隆首都雅温得从1975年开始采用三价口服脊髓灰质炎疫苗实行计划免疫。1975年雅温得的麻痹型脊髓灰质炎发病率为66/10万,1979年为10/10万,下降了85%。对221名12～23月龄儿童的调查表明,至少服过两剂疫苗者占45%,服过3剂者仅占35%。对91名2～11月龄的服苗儿童进行血清学调查表明,服苗前67%的儿童抗体阴性;4%的儿童具有3个型病毒的中和抗体。33名儿童口服第2剂疫苗后30天,33%的儿童对3个型病毒的抗体仍为阴性,只有21%的儿童产生3对所有3个型的抗体,分别有36%、
Yaoundé, the capital of Cameroon, started the planned immunization with trivalent oral polio vaccine in 1975. The incidence of paralytic poliomyelitis in Yaoundé in 1975 was 66/10, down from 10/10 in 1979 to 85%. A survey of 221 children aged 12 to 23 months showed that at least 45% of those who took two doses of the vaccine had only 35% of those who took the three doses. A serological survey of 91 children aged 2 to 11 months showed that 67% of children were negative before taking vaccine and 4% had neutralizing antibodies against 3 viruses. Thirty days after oral administration of the second vaccine to 33 children, 33% of the children were still negative for the three viruses and only 21% of the children had 3 pairs of all three antibodies, 36%