足月新生儿大约在生后72小时血清胆红素的浓度达到最高值,而病理性黄疸(血清胆红素浓度>12.0mg％)的发生率约为5％。由于多种原因,许多婴儿在生后48小时就已出院。这样,有些婴儿的血清胆红素浓度在出院后就有升高的潜在危险。作者应用以下两种非损伤性检查,试图预测那些在生后第1周内可能发生病理性黄疸的病例。方法,一氧化碳浓度(ETco)的测定:在血红素的分解代谢过程中,CO产生的克分子量和胆红素产生的量相等。因此,ETco可作为胆红素产量的指标。具体方法与以往 Full-term neonatal serum bilirubin reaches its peak at about 72 hours after birth, whereas the incidence of pathological jaundice (serum bilirubin concentration> 12.0 mg%) is about 5%. Many infants have been discharged from hospital 48 hours after birth for a number of reasons. In this way, some babies have a potentially elevated serum bilirubin concentration after discharge. The authors applied the following two noninvasive exams to try to predict cases of pathologic jaundice that could occur during the first week of life. Method, determination of carbon monoxide concentration (ETCO): During catabolism of heme, CO produces the same molar mass as bilirubin production. Therefore, ETco can be used as an indicator of bilirubin production. Specific methods and past