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目的：为了评价生长抑素对急性胰腺炎的疗效。方法：４８例确诊为急性胰腺炎患者随机分为：对照组２５例，给予常规治疗；治疗组２３例，在常规治疗基础上加用生长抑素２５０μｇ／ｈ持续静脉滴注，疗程３～１４ｄ。结果：治疗组腹痛缓解时间明显快于对照组，其差异有非常显著意义（Ｐ＜０００１）；重要实验室指标血白细胞，淀粉酶、乳酸脱氢酶治疗组降低幅度大于对照组，其差异有显著性（Ｐ＜００５）；治疗组并发症发生率少于对照组，但无统计学意义。结论：生长抑素可明显缓解急性胰腺炎患者腹痛症状，并有阻止病情严重化，减少并发症之趋势。
Objective: To evaluate the effect of somatostatin on acute pancreatitis. Methods: Forty-eight patients diagnosed as acute pancreatitis were randomly divided into control group (n = 25) treated with conventional therapy and treatment group (n = 23) treated with continuous infusion of somatostatin 250μg / h on the basis of routine treatment for 3-14 days . Results: The pain relief time of the treatment group was significantly faster than that of the control group, the difference was significant (P <0001). Significant laboratory indexes of white blood cells, amylase, lactate dehydrogenase treatment group decreased more significantly than the control group The difference was significant (P <0 05); the incidence of complications in the treatment group less than the control group, but not statistically significant. Conclusion: Somatostatin can significantly relieve the symptoms of abdominal pain in patients with acute pancreatitis, and prevent the serious condition and reduce the tendency of complications.