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选择21例应用预混人胰岛素Novolin 30R治疗血糖控制欠佳的1型和2型糖尿病患者,用胰岛素泵交叉应用相同剂量的速效人胰岛素类似物Aspart与正规人胰岛素NovolinR控制高血糖,比较两种药物应用期间全天毛细血管血糖谱,发现Aspart在控制空腹血糖、餐后血糖及全天平均血糖均较后者疗效为佳。
21 patients with type 1 and type 2 diabetes with poor glycemic control were treated with 21 mL of pre-mixed insulin Novolin 30R. Hyperglycemia was controlled by insulin pump with the same dosage of fast acting human insulin Aspart and normal human insulin NovolinR. All-day capillary blood glucose profile during drug use found that Aspart was superior to the latter in controlling fasting blood glucose, postprandial blood glucose, and mean daily blood glucose.