平滑肌细胞增生及移位导致内膜增生，是影响移植血管远期通畅率的关键问题。研究大鼠颈静脉移植于腹主动脉后，普卡霉素抑制移植静脉内膜增生的作用。１　材料与方法１．１　主要试剂　普卡霉素（Ｓｉｇｍａ），５′－溴脱氧尿苷（５′－Ｂｒｄｕ，０．１ｇ，中科院上海生化所 Smooth muscle cell proliferation and translocation lead to intimal hyperplasia, which is the key issue affecting the long-term patency of transplanted blood vessels. To study the effect of plicamycin on the intimal hyperplasia of vein graft after the transplantation of rat jugular vein in the abdominal aorta. 1 Materials and methods 1.1 The main reagents penicillin (Sigma), 5’-Bromodeoxyuridine (5’-Brdu, 0.1g, Shanghai Institute of Biochemistry