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以往,人类月经周期中卵巢的形态学变化往往是通过内分泌和临床指标间接进行推测的。例如通过测定雌二醇和孕酮来估价卵巢甾体激素的分泌情况;通过基础体温和宫颈变化预测排卵;应用放射免疫测定法和放射受体测定法测定血中LH浓度,进而预测排卵并通过剖腹术予以证实。至今,除外科手术外,临床医生尚无法通过上述手段区分成熟卵泡破裂前内膜细胞是否已发生黄体化。本文工作用超声波检测卵泡直径,并分析了与雌二醇和LH水平的关系。对单卵泡和双卵泡生长时雌二醇水平的变化也进行了分析。选择20名正常月经周期的妇女(21～36)岁,在LH峰前的第9、5、3、2、1天和当天的9时至11时分别取血,用放射免疫分析法测定血清
In the past, ovarian morphological changes in human menstrual cycle are often speculated indirectly through the endocrine and clinical indicators. For example by measuring estradiol and progesterone to estimate the secretion of ovarian steroid hormones; predicting ovulation by basal body temperature and cervical changes; determining blood LH levels by radioimmunoassay and radioimmunoassay to predict ovulation and by cesarean section Surgery to be confirmed. So far, in addition to surgery, clinicians can not distinguish between the above means before the rupture of mature follicular endometrial cells have occurred in the corpus luteum. In this work, we examined the follicular diameter using ultrasound and analyzed the relationship with estradiol and LH levels. Changes in estradiol levels during single and double follicle growth were also analyzed. Twenty women (21-36 years) with normal menstrual cycle were enrolled in the study. Blood samples were taken before 9th, 5th, 3rd, 2nd and 1st day of LH peak and from 9:00 to 11:00 of the day before the peak of LH. Serum was measured by radioimmunoassay