自从1985年由Benaceraff等[1]报道了21-三体综合征(简称21-三体,下同)颈后透明层(NT)增厚病例以来,NT作为21-三体的早期预测指标已普遍得到公认。最近几年许多研究报道了胎儿鼻骨测量的方法以及三体综合征胎儿鼻骨的超声表现异常(鼻骨缺失和发育不良),预示了通过超声检查胎儿鼻 Since 1985, Benaceraff et al [1] reported 21 cases of trisomy 21 (trisomy, the same below) the thickness of the posterior cervical transparent layer (NT), NT as a trisomy 21 early predictors Generally accepted. In recent years, many studies have reported fetal nasal bone measurement methods and trisomy fetal nasal bone ultrasound abnormalities (nasal bone loss and hypoplastic), foreshadowed by fetal ultrasound examination of the nose